Adam Kohn

Assistant Professor
Visual neuroscience; cortical plasticity

Kennedy Center
Room 821
(718) 430-2417
akohn@aecom.yu.edu

 


Our laboratory studies the neural circuits that underlie visual perception, a general issue that we approach from several directions.  For instance, we study how the responsivity and tuning of cortical neurons is altered by recent stimulus history.  This form of rapid plasticity--termed adaptation--has strong perceptual effects, allowing us to explore the neurophysiological underpinnings of perceptual phenomena.  In addition, we are interested in understanding the functional benefit of adaptation and in learning how adaptation early in the visual system affects subsequent stages of processing.  We hope that by understanding the principles of adaptation we will also gain insight into other forms of plasticity such as perceptual learning and recovery from injury.  We also study how populations of neurons function together to encode information about the visual world.  We record from small populations of neurons simultaneously and measure the correlation of their responses.  In particular, we explore how correlation depends on stimulus parameters, recent stimulus history, and cortical location.  The primary techniques of the lab are neurophysiological recordings and computational modeling, but also include psychophysics and functional imaging.  We hope that employing a range of experimental techniques will help us understand the computations carried out by the visual system and the circuits that perform them.

Selected Publications

Smith MA, Kohn A (2008)  Spatial and temporal scales of neuronal correlation in primary visual cortex.  Journal of Neuroscience 28: 12591-12603.

Kohn A (2007) Visual adaptation: physiology, mechanisms, and functional benefits.  Journal of Neurophysiology 97: 3155-3164.

Montani F, Kohn A, Smith MA, Schultz SR (2007) The role of correlations in direction and contrast coding in the primary visual cortex.  Journal of Neuroscience 27: 2338-2348.

Kelly RC, Smith MA, Samonds JM, Kohn A, Bonds AB, Movshon JA, Lee TS (2007) Comparison of recordings from microelectrode arrays and single electrodes in visual cortex.  Journal of Neuroscience 27: 261-264.

Kohn A and Smith MA (2005) Stimulus dependence of neuronal correlation in primary visual cortex of the macaque. Journal of Neuroscience 25: 3661-3673.

Kohn A and Movshon JA (2004) Adaptation changes the direction tuning of macaque MT neurons.  Nature Neuroscience 7: 764-772.

Kohn A and Movshon JA (2003) Neuronal adaptation to visual motion in area MT of the macaque.  Neuron 39: 681-691.

Kohn A and Whitsel BL (2002) Sensory Cortical Dynamics. Behavioral Brain Research 135: 119-126.

Kohn A, Metz C, Tommerdahl MA and Whitsel BL (2002) Dynamic stimulus-evoked modulation of sensorimotor pyramidal neuron EPSPs. Journal of Neurophysiology 88: 3331-3347.